RenardV1, Main, Exploration, bibRecord, 000628

Scenario-analysis evaluating semergency strategies after rabies re-introduction.

Identifieur interne : 000628 ( Main/Exploration ); précédent : 000627; suivant : 000629

Scenario-analysis evaluating semergency strategies after rabies re-introduction.

Auteurs : H-H Thulke [Allemagne] ; D. Eisinger ; T. Selhorst ; T. Müller

Source :

Developments in biologicals [ 1424-6074 ] ; 2008.

RBID : pubmed:18634488

English descriptors

KwdEn :
- Administration, Oral, Animals, Computer Simulation, Disease Outbreaks (prevention & control), Disease Outbreaks (veterinary), Female, Foxes (virology), Male, Models, Biological, Rabies (epidemiology), Rabies (immunology), Rabies (prevention & control), Rabies (veterinary), Rabies Vaccines (administration & dosage), Rabies Vaccines (economics), Rabies Vaccines (immunology), Risk Assessment.
MESH :
- chemical , administration & dosage : Rabies Vaccines.
- chemical , economics : Rabies Vaccines.
- epidemiology : Rabies.
- immunology : Rabies, Rabies Vaccines.
- prevention & control : Disease Outbreaks, Rabies.
- veterinary : Disease Outbreaks, Rabies.
- virology : Foxes.
- Administration, Oral, Animals, Computer Simulation, Female, Male, Models, Biological, Risk Assessment.

Abstract

Now that the elimination of rabies in Western Europe is nearly complete, thanks to the oral mass vaccination of foxes (ORV) which took place over the last 25 years, it is necessary to prepare for emergency situations due to the re-introduction of rabies from still infected areas. Such emergency strategies should aim at minimizing the risk of falling back to large-scale vaccination, in a cost efficient manner. An approved spatially-explicit simulation model of spread and control of rabies was adapted to the new problem of re-introduction of rabies into free areas. The logic of the model and options for local emergency vaccination (for example ring-vaccination vs. compact area treatment or heavily concentrated vs. thin extended control areas) were determined. Based on systematic simulation experiments the performance of strategic options was assessed. Key issues such as public health risk (i.e. number of rabies cases), failure risk (i.e. disease breakout from the control area), and budgetary risk (i.e. duration of the emergency program) were simultaneously considered. The results obtained reveal efficiency relations that contradict a priori derived management suggestions.

PubMed: 18634488

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Now that the elimination of rabies in Western Europe is nearly complete, thanks to the oral mass vaccination of foxes (ORV) which took place over the last 25 years, it is necessary to prepare for emergency situations due to the re-introduction of rabies from still infected areas. Such emergency strategies should aim at minimizing the risk of falling back to large-scale vaccination, in a cost efficient manner. An approved spatially-explicit simulation model of spread and control of rabies was adapted to the new problem of re-introduction of rabies into free areas. The logic of the model and options for local emergency vaccination (for example ring-vaccination vs. compact area treatment or heavily concentrated vs. thin extended control areas) were determined. Based on systematic simulation experiments the performance of strategic options was assessed. Key issues such as public health risk (i.e. number of rabies cases), failure risk (i.e. disease breakout from the control area), and budgetary risk (i.e. duration of the emergency program) were simultaneously considered. The results obtained reveal efficiency relations that contradict a priori derived management suggestions.</div>
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Scenario-analysis evaluating semergency strategies after rabies re-introduction.

Scenario-analysis evaluating semergency strategies after rabies re-introduction.

Source :

English descriptors

Abstract

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Le document en format XML

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